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. 2021 May 24;8:654635. doi: 10.3389/fmed.2021.654635

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Copyright © 2021 Shen, Xiong, Gu, Zhang, Yue, Liu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Multi-omics clustering analysis of CNV, DNA methylation and mRNA expression. (A) iCluster clustering heat map showing the CNV distribution of CNVcor genes. (B) iCluster clustering heat map showing the methylation site distribution of METcor genes. (C) Kaplan-Meier survival analysis results for two subtypes. (D) Intersection of NMF and iCluster CNVcor gene sets. (E) Overlap between NMF METcor gene subsets and iCluster METcor subsets. (F) Overlap between iCluster METcor gene subsets and iCluster CNVcor gene subsets.