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. 2021 Jun 4;100(22):e26194. doi: 10.1097/MD.0000000000026194

Table 1.

Results of the top 10 GO terms and the top 10 KEGG pathway analyses.

Category Term Description Gene counts LogP
Upregulated DEGs
 GO: 0051301 BP Cell division 23 −11
 GO: 0007059 BP Chromosome segregation 17 −10
 GO: 0006260 BP DNA replication 15 −9.4
 GO: 0000228 CC Nuclear chromosome 19 −7.8
 GO: 0098813 BP Nuclear chromosome segregation 13 −7.7
 GO: 0045786 BP Negative regulation of cell cycle 19 −7.4
 GO: 0000819 BP Sister chromatid segregation 11 −7.3
 GO: 0098687 CC Chromosomal region 14 −7.2
 GO: 0000280 BP Nuclear division 15 −7.1
 GO: 0044454 CC Nuclear chromosome part 17 −6.7
 hsa04110 KEGG Cell cycle 6 −3.8
 hsa05215 KEGG Prostate cancer 5 −3.6
 hsa05224 KEGG Breast cancer 6 −3.5
 hsa05230 KEGG Central carbon metabolism in cancer 4 −3.1
 hsa05216 KEGG Thyroid cancer 3 −3.1
 hsa05218 KEGG Melanoma 4 −3
 hsa05200 KEGG Pathways in cancer 9 −3
 hsa05219 KEGG Bladder cancer 3 −2.6
 hsa03440 KEGG Homologous recombination 3 −2.6
 hsa05161 KEGG Hepatitis B 5 −2.6
Downregulated DEGs
 GO: 0046951 BP Ketone body biosynthetic process 2 −5.3
 GO: 0046950 BP Cellular ketone body metabolic process 2 −5.1
 GO: 0032230 BP Positive regulation of synaptic transmission, GABAergic 2 −5
 GO: 1902224 BP Ketone body metabolic process 2 −5
 GO: 0032228 BP Regulation of synaptic transmission, GABAergic 2 −4.1
 GO: 0051932 BP Synaptic transmission, GABAergic 2 −3.8
 GO: 0099617 CC Matrix side of mitochondrial inner membrane 1 −3.4
 GO: 0001985 BP Negative regulation of heart rate involved in baroreceptor response to increased systemic arterial b 1 −3.4
 GO: 0001983 BP Baroreceptor response to increased systemic arterial blood pressure 1 −3.4
 GO: 0001978 BP regulation of systemic arterial blood Pressure by carotid sinus baroreceptor feedback 1 −3.4
 hsa00072 KEGG Synthesis and degradation of ketone bodies 2 −5.2
 hsa00650 KEGG Butanoate metabolism 2 −4.2
 hsa04976 KEGG Bile secretion 2 −3.4
 hsa00910 KEGG Nitrogen metabolism 1 −2.2
 hsa04964 KEGG Proximal tubule bicarbonate reclamation 1 −2
 hsa04966 KEGG Collecting duct acid secretion 1 −2
 hsa05219 KEGG Bladder cancer 1 −1.8
 hsa05144 KEGG Malaria 1 −1.7
 hsa05150 KEGG Staphylococcus aureus infection 1 −1.6
 hsa04115 KEGG p53 signaling pathway 1 −1.5