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Dantrolene significantly decreases phosphorylation of ryanodine receptor (RyR) in MI-induced heart failure rats. A: Representative immunoblots of phosphorylated and total RyR2 in left ventricular tissue from different groups. B: Quantification of intensity of bands in protein expression levels. Data are given as mean ± SD (n = 6). ∗P <.05 vs sham. #P <.05 vs MI-vehicle. MI = myocardial infarction.
