Table 2.

Demographics and echocardiographic measurements

	Normal			HTN			LVH			HFpEF			F test P values ANOVA
	C	AA	P	C	AA	P	C	AA	P	C	AA	P	Race P value	Disease P value	Race × disease P value
Age, years	53 ± 16	52 ± 12	.676	61 ± 10	54 ± 11†	<.01	63 ± 11	56 ± 11∗	<.001	67 ± 13	65 ± 11	.448	<.01∗	<.001∗	.284
6-min walk, m	398 ± 113	363 ± 84	.161	389 ± 78	363 ± 59	.179	367 ± 76	374 ± 114	.656	214 ± 107	237 ± 98	.415	0.481	<.001∗	.246
BSA, m2	1.8 ± 0.2	2.0 ± 0.2†	<.01	1.9 ± 0.3	2.0 ± 0.3	.367	2.0 ± 0.3	2.1 ± 0.3	.171	2.1 ± 0.3	2.1 ± 0.3	.709	<0.01∗	<.001∗	.389
SBP, mm Hg	123 ± 13	126 ± 10	.267	131 ± 13	133 ± 9	.569	134 ± 11	135 ± 11	.685	137 ± 20	143 ± 15	.073	0.037∗	<.001∗	.589
DBP, mm Hg	74 ± 8	76 ± 7	.171	78 ± 8	78 ± 7	.926	79 ± 7	81 ± 10	.115	76 ± 10	78 ± 8	.283	0.053	<.001∗	.631
LA diam, cm	3.51 ± 0.48	3.65 ± 0.33	.228	3.79 ± 0.34	3.59 ± 0.43†	.044	4.17 ± 0.52	3.91 ± 0.53†	<.001	4.31 ± 0.53	3.97 ± 0.35†	<.01	<0.01∗	<.001∗	.017∗
LVEF, %	67 ± 5	69 ± 5	.214	70 ± 6	65 ± 7†	<.001	69 ± 7	68 ± 7	.462	69 ± 7	68 ± 8	.512	.125	.671	.017∗
LV Massi, g/m2	79 ± 15	74 ± 15	.207	81 ± 16	78 ± 15	.437	117 ± 23	110 ± 14†	.015	129 ± 29	111 ± 18†	<.001	<.001∗	<.001∗	.105
LV EDVi, mL/m2	54 ± 11	50 ± 8	.143	53 ± 10	49 ± 11	.071	55 ± 12	48 ± 10†	<.001	56 ± 14	48 ± 10	.013	<.001∗	.878	.652
RWTd, cm/cm	0.40 ± 0.07	0.39 ± 0.06	.862	0.40 ± 0.05	0.42 ± 0.07	.131	0.51 ± 0.08	0.53 ± 0.07†	.044	0.55 ± 0.10	0.56 ± 0.11	.652	.104	<.001∗	.571
E, cm/sec	68 ± 17	74 ± 16	.082	68 ± 15	71 ± 15	.486	64 ± 17	65 ± 15	.864	76 ± 17	71 ± 13	.1969	.585	<.01∗	.197
A, cm/sec	66 ± 18	70 ± 15	.437	80 ± 15	76 ± 16	.359	78 ± 15	79 ± 19	.837	90 ± 24	87 ± 22	.561	.791	<.001∗	.621
E′, mm/sec	10.7 ± 3.2	11.1 ± 2.6	.517	9.7 ± 2.4	9.8 ± 2.3	.788	9.0 ± 2.3	8.8 ± 2.4	.626	7.0 ± 1.8	6.8 ± 1.9	.762	.916	<.001∗	.844
E/E′	6.4 ± 1.6	6.9 ± 1.7	.337	7.3 ± 1.8	7.3 ± 1.5	.901	7.4 ± 2.1	7.7 ± 2.3	.371	11.7 ± 3.9	11.4 ± 4.2	.608	.548	<.001∗	.731
Sample size, n	119	20		86	33		84	55		37	21

A= late diastolic filling velocity (atrial contraction); AA = African Americans; BSA = body surface area; C = Caucasians; DBP = diastolic blood pressure; E = peak early filling velocity (rapid filling); EDV = end-diastolic volume; HFpEF = heart failure with preserved ejection fraction; HTN = hypertension; LA = left atrium; LVEF = left ventricular ejection fraction; LVH = left ventricular hypertrophy; RWTd = relative wall thickness at end diastole; SBP = systolic blood pressure.

Data are mean ± SD unless otherwise indicated.

Asterisk indicates statistically significant P values.

^†P < .05 vs corresponding Caucasian.