Table 2.

Primary and secondary outcomes in propensity-matched cohort

	No ablation	Ablation	P value
HFrEF
Patients (n)	3614	1807
Primary outcome at 1 year (%)†	14.5	10.7	<.001
Primary outcome at 1 year (HR, 95% CI)‡	0.72 (0.61 – 0.85)		<.001
HF readmission at 1 year (%)†	10.8	8.2	<.001
HF readmission at 1 year (HR, 95% CI)‡	0.73 (0.61 – 0.89)		.001
Mortality at 1 year (%)†	4.5	2.8	.003
Mortality at 1 year (HR, 95% CI)‡	0.62 (0.46 – 0.85)		.003
AF readmission at 1 year (%)†	6.2	4	.001
AF readmission at 1 year (HR, 95% CI)‡	0.63 (0.48 – 0.82)		.001
Any readmission at 1 year (%)†	37.9	29.7	<.001
Any readmission at 1 year (HR, 95% CI)‡	0.72 (0.65 – 0.80)		<.001
AFL readmission at 1 year (%)†	6.4	1.8	<.001
AFL readmission at 1 year (HR, 95% CI)‡	0.27 (0.19 – 0.39)		<.001
HFpEF
Patients (n)	1626	813
Primary outcome at 1 year (%)†	14.7	12.1	.065
Primary outcome at 1 year (HR, 95% CI)‡	0.8 (0.63 – 1.01)		.065
HF readmission at 1 year (%)†	11.2	9.6	.187
HF readmission at 1 year (HR, 95% CI)‡	0.84 (0.64 – 1.09)		.187
Mortality at 1 year (%)†	4.5	3.2	.117
Mortality at 1 year (HR, 95% CI)‡	0.7 (0.45 – 1.1)		.119
AF readmission at 1 year (%)†	7.3	5.7	.107
AF readmission at 1 year (HR, 95% CI)‡	0.76 (0.54 – 1.06)		.108
Any readmission at 1 year (%)†	43.1	37.5	.003
Any readmission at 1 year (HR, 95% CI) ‡	0.82 (0.71 – 0.94)		.003
AFL readmission at 1 year (%)†	5.9	2.2	<.001
AFL readmission at 1 year (HR, 95% CI)‡	0.36 (0.22 – 0.60)		<.001

AF = atrial fibrillation; AFL = atrial flutter; CI = confidence interval; HF = heart failure; HFpEF = heart failure with preserved ejection fraction; HFrEF = heart failure with reduced ejection fraction; HR = hazard ratio.

^†Log-rank test.

^‡Cox proportional regression models: Individual models were run for ablation as an outcome.