Table.
Country and month/year | Number of cases | Age (yr/gender) | Comorbid conditions | Abnormal laboratory parameters | Radiological findings | Treatment | Outcome |
---|---|---|---|---|---|---|---|
Wuhan, China, January 202015 | One | 69, male | None | Leucopenia and lymphopenia | CT scan report - Mass, ground-glass consolidation in the right inferior lobe of the lungs | Oral oseltamivir ICU - Endotracheal intubation | Transferred |
Tokyo, Japan, February 202016 | One | 78, female | Dyslipidaemia, hypothyroidism | Elevated liver enzymes | CT scan report - Ground- glass opacity adjacent to pleura Chest X-rays - Bilateral reticular shadow | Oral oseltamivir | Discharged |
Barcelona, Spain, 202017 | Three | 53, male (P1) 78, male (P2) 56, male (P3) | All patients had hypertension P1 - End-stage renal disease (on dialysis) P2 - Type 2 diabetes mellitus | P1 - Elevated CRP. Ferritin, D-dimer P2 - Elevated CRP, LDH, D-dimer P3 - Elevated CRP, LDH, D-dimer | Chest X-rays - P2 - Bilateral infiltrate | P1, P2 - Mechanical ventilation Lopinavir-ritonavir 400/100 mg twice a day, oral HCQ 200 mg twice a day (in haemodialysis patients, 100 mg twice a day) and oral oseltamivir 150 mg twice a day (in haemodialysis patients, 30 mg every 48 h). Subcutaneous interferon β-1b 8 MU was added every 48 h in P2 | P3 - Discharged after 48 h |
Rome, Italy, March 202018 | One | 56, male | Overweight, history of myocardial infarction | Lymphopenia, CRP, fibrinogen elevated | CT scan report - Bilateral peripheral ground-glass opacities | ICU - Non-invasive ventilation Oral oseltamivir (75 mg twice per day for five days) and lopinavir/ritonavir (400/100 mg twice per day for 14 days) Intravenous methylprednisolone (40 mg twice daily for five days with tapered discontinuation) | Discharged |
Kentucky, USA, 202013 | One | 66, female | Hypertension, diabetes, chronic kidney disease Stage 3, congestive heart failure, coronary artery disease | - | Chest X-ray - Right lower lobe infiltrate | ICU - Ventilated Oral Tamiflu® 30 mg twice a day for five days HCQ | Not mentioned |
Istanbul, Turkey, March-May, 202019 | Two | P1-49, female P2-51, male | P2 - Diabetes mellitus | P2 - Ferritin elevated | CT scan report - Bilateral peripheral ground-glass opacities | HCQ, azithromycin, oseltamivir | Discharged |
Wuhan, China, September, 202020 | Three | P1-47, female P2-50, male P3-49, female | P2 - Hypertension | P1 and P2 - Lymphopenia CRP elevated in P1, P2 and P3 | CT scan report - Pulmonary lesions | Oral oseltamivir Glucocorticoid therapy P2 - Non-invasive ventilation | Discharged |
Bojnurd, Iran, March-April, 202012 | Two | P1-78, female P2-75, male | P1 - Chronic lung disease | P1 and P2 - Lymphopenia | CT scan report - Bilateral peripheral ground-glass opacities | ICU Combination HCQ and Kaletra® (lopinavir/ritonavir) | P1 and P2 expired |
CRP, C-reactive protein; CT, computed tomography; ICU, intensive care unit; HCQ, hydroxychloroquine; LDH, lactate dehydrogenase