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. 2021 Jan-Feb;153(1-2):166–174. doi: 10.4103/ijmr.IJMR_3418_20

Table II.

Synonymous and non-synonymous substitutions characterizing the dominant Phylogenetic Assignment of Named Global Outbreak LINeages (Pangolin) in India

Pangolin lineage Synonymous substitution Non-synonymous substitutions Untranslated nucleotide change


Nucleotide variation Gene (amino-acid change) Nucleotide variation Gene (amino-acid change)
B.1.113 C22444T S (D294D) C28854T N (S194L) -
B.1.1.32 C313T NSP1 (L16L) C5700A nsp3 (A994D)/ORF1ab (A1812D) -
B.1.1.8 G4354A NSP3 (E545E)/ORF1ab (E1363E) C6573T nsp3 (S1285F)/ORF1ab (S2103F) -
C25528T ORF3a (L46F)
B.1.80 C3634T NSP3 (N305N)/ORF1ab (N1123N) -
C15324T NSP12b (N619N)
B.4 T28688C N (A138A) C884T nsp2 (R27C)/ORF1ab (R207C) 3’UTR (G29742T)
G1397A nsp2 (V198I)/ORF1ab (V378I)
G8653T nsp4 (M33I)/ORF1ab (M2796I)
G11083T nsp6 (L37F)/ORF1ab (L3606F)
B.6 C13730T nsp12b (A88V) -
C28311T N (P13L)
C6312A nsp3 (T1198K)/ORF1ab (T2016K)
G11083T nsp6 (L37F)/ORF1ab (L3606F)