Table 1.

Summary of Number of Genes Reaching Cut Offs (Fold Change >1.5 and P<0.05) from the Predefined Gene List, and Entire Gene Array in Sputum and Blood

Comparison	Sputum Gene Changes Predefined List	Sputum Gene Changes Total Set	Blood Gene Changes Total Set
Screening vs D12 nemiralisib	29	1383	336
Screening vs D12 placebo	35	1395	90
Screening vs D28 nemiralisib	3	350	204
Screening vs D28 placebo	1	329	302
Screening vs D84 nemiralisib	15	690	529
Screening vs D84 placebo	29	1096	590
D84 nemiralisib vs D84 placebo	10	297	253

Abbreviations: D12, Day 12; D84, Day 84.