Table 4.

Statistical Results of the Comparison between the Patients vs. the Healthy Individuals for the Examined miRNAs

miRNA	AUC*	95% CI**	cutoff level	Y-index***	Std. Error***	sensitivity	specifity
miR-145-5p	0.95	0.870-1.035	0.034	0.85	0.042	90%	95%
miR-185-5p	0.87	0.763-0.979	0.715	0.58	0.055	63%	95%

* AUC: an area under the ROC curve; **, CI 95%: 95% confidential interval; ***, The Y-index was used to judge the most appropriate critical point. It was calculated as follow (1-[sensitivity+ specifity]); ****, Std. Error: under the non-parametric assumption.