Figure 1.

Effects of FAK Inhibitor and Cucurbitacin B on Cell Viability and FAK Activation in CCA Cells. KKU-452 cells were treated with designated compounds for 24 h. Thereafter, the cell viability of (A) FAK inhibitor-14- and (B) cucurbitacin B-treated cells was evaluated using sulforhodamine B assay. Activation of FAK in cells treated with (C) FAK inhibition-14 or (D) cucurbitacin B was determined using Western blot analysis. Representative images and quantification graphs are shown. Data are expressed as mean ± SD of three independent experiments. *, p < 0.05 vs respective control