Table 1.
Comparison between PVT Cases and Controls Regards Routine Laboratory Variables
| Parameters | PVT Cases (N=100) | Healthy controls (N=100) | p-value | |
|---|---|---|---|---|
| Age (years) | Mean± SD | 58.3± 6.3 | 49.3± 3.6 | |
| Min-max | 33-68 | 35-61 | 0.32 | |
| HB (g/dl) | Median (IQR) | 11.0 (3.0) | 13.0 (1.0) | <0.001 |
| Min-max | 7-16 | 11-17 | <0.001 | |
| WBCs (x103) | Median (IQR) | 9.0 (4) | 7.0 (2) | <0.001 |
| Min-max | 3-19 | 4-10 | <0.001 | |
| Platelets (x103) | Median (IQR) | 169.0 (160) | 276.5 (149) | <0.001 |
| Min-max | 50-519 | 182-441 | <0.001 | |
| ALT (IU/L) | Median (IQR) | 33.0 (39) | 18.5 (12) | <0.001 |
| Min-max | 6-735 | 10-29 | <0.001 | |
| AST (IU/L) | Median (IQR) | 52.0 (79) | 19.0 (8) | <0.001 |
| Min-max | 8-2248 | 10-29 | <0.001 | |
| GGT (IU/L) | Median (IQR) | 66.0 (102) | 19.0 (5) | <0.001 |
| Min-max | 12-534 | 10-32 | <0.001 | |
| ALK ph (IU/L) | Median (IQR) | 132.0 (77) | 59.0 (23) | <0.001 |
| Min-max | 44-990 | 31-99 | 0.24* | |
| Albumin (g/dl) | Median (IQR) | 3.0 (1.6) | 4.0 (0.3) | <0.001 |
| Min-max | 1-5 | 4-4.9 | ||
| T. Bilirubin (mg/dl) | Median (IQR) | 2.0 (7.0) | 0.4 (0.2) | <0.001 |
| Min-max | 0.3-25 | 0.2-1 | ||
| INR | Median (IQR) | 1.4 (0.5) | 1.0 (0.03) | <0.001 |
| Min-max | 1-2.3 | 0.9-1.1 | ||
| Urea (mg/dl) | Median (IQR) | 64.0 (112) | 32.0 (6.0) | <0.001 |
| Min-max | 20.0-214.0 | 23.0-42.0 | ||
| Creatinine (mg/dl) | Median (IQR) | 1.1 (0.7) | 0.7 (0.1) | <0.001 |
| Min-max | 0.6-4.6 | 0.6-0.99 | ||
| AFP (ng/ml) | Median (IQR) | 72.2 (6647.3) | 2.35 (1) | <0.001 |
| Min-max | 0.73 - 150218.0 | 1.5-6.2 | ||
| MTHFR | Wild | 58 (58) | 66 (66) | 0.24* |
| Heterozygous | 42 (42) | 34 (34) |
LA, lupus anticoagulant; ACL, anticardiolipin; DAAS, direct acting antiviral drugs, FVL, factor V Leiden; MTHFR, methyl-tetrahydrofolate reductase; P>0.05 is non-significant; p <0.05: is significant; *Chi square test (x2) is used.