Figure 1.

Experimental design.

Notes: (A) An illustration of the design and fabrication process of the scaffold. A blend of GO and PCL was firstly electrospun to fabricate outer scaffold (GO-PCL). Next, the inner scaffold (CS-PCL) was sprayed directly on the surface of GO-PCL scaffold to obtain a double-layer scaffold (GO-PCL/CS-PCL). The prepared GO-PCL/CS-PCL scaffold was immersed in NAC-EDC/NHS solution and crosslinked to obtain a final scaffold (GO-PCL/NAC-CS-PCL). (B) Illustration of GO-PCL/NAC-CS-PCL scaffold and its application in the reconstruction of full-thickness abdominal wall defect (2.0cm×1.5cm) in rats.