Table 2.
Comparisons of the FAF and OCT findings between early-acute, subacute, and early-chronic CSC patients.
| Acute CSC (n = 8) | Early-chronic CSC (n = 34) | Late-chronic CSC (n = 27) | p value | |
|---|---|---|---|---|
| Age (years) | 40 ± 14.6 | 52.6 ± 8.6 | 54.2 ± 10.9 | 0.028∗b 0.05∗c3 |
|
| ||||
| Visual acuity (LogMAR) | 0.057 ± 0.27 | 0.111 ± 0.26 | 0.38 ± 0.39 | 0.034∗b 0.033∗c3 |
|
| ||||
| Choroidal layer thickness (μm) | 364 ± 138.9 | 319 ± 47.7 | 337 ± 54.6 | 0.548 b |
|
| ||||
| FAF findings at leakage site | ||||
| Discrete hypo-FAF spot | 8 (100%) | 21 (61.8%) | 14 (51.9%) | 0.044∗a |
| Indistinct pattern at leakage site | 0 | 13 (38.2%) | 13 (48.1%) | |
|
| ||||
| Background FAF findings | ||||
| Hyper-FAF | 8 (100%) | 28 (82.4%) | 17 (63%) | 0.020∗a |
| Hypo-FAF | 0 | 0 | 6 (22.2%) | |
| Mixed-pattern AF | 0 | 6 (17.7%) | 4 14.8%) | |
|
| ||||
| OCT findings-RPE abnormalities | ||||
| Type 1: semicircular peaked PED | 4 (50%) | 11 (32.4%) | 2 (7.4%) | 0.025∗a |
| Type 2: low-lying PEDs | 4 (50%) | 8 (23.5%) | 5 (18.5%) | |
| Type 3: flat irregular PEDs | 11 (32.3%) | 9 (33.3%) | ||
| Type 4: RPE irregularity without definite PED | 4 (11.8%) | 11 (40.7%) | ||
|
| ||||
| Height of PEDs (μm) | 133.3 ± 57.4 | 70.0 ± 5.62 | 72.1 ± 17.5 | 0.329 c1 0.028∗c2 |
| Width of PEDs (μm) | 367.5 ± 139.2 | 499.3.0 ± 182.6 | 1297.9 ± 728.8 | 0.004∗b |
|
| ||||
| Abnormalities of outer retina | ||||
| Length of the photoreceptor (IS/OS) layer (μm) | 79.0 ± 13.3 | 72.8 ± 29.5 | 55.2 ± 19.9 | 0.017∗b |
|
| ||||
| Presence of elongation or thinning of OS photoreceptor | ||||
| Elongation | 1 | 2 | 1 | 0.002∗a |
| Normal thickness | 5 | 6 | 6 | |
| Thinning | 0 | 1 | 14 | |
|
| ||||
| Presence of subretinal precipitates | 1 | 1 | 11 | 0.001∗a |
|
| ||||
| Presence of fibrinous exudates | 6 | 9 | 22 | 0.001∗d |
aFisher's exact test. bANOVA test (analysis of variance test). c1t-test comparing acute and early-chronic groups. c2t-test comparing early-chronic and late-chronic groups. c3t-test comparing acute and late-chronic groups. dChi-Square test. ∗, p value less than 0.005, with statistically significant result observed.