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. 2021 May;9(10):835. doi: 10.21037/atm-20-7883

Table 2. Statistical difference analysis of clinical and laboratory features between acute purulent appendicitis and gangrenous or perforated appendicitis.

Variable Sample Acute purulent appendicitis Gangrenous or perforated appendicitis Statisticsa P value
Age (years, mean ± SD) 127 42.16±17.34 40.54±15.31 0.419 0.676
Gender
   M 68 56 (53.40%) 12 (54.17%) 0.005 0.948
   F 59 48 (46.15%) 11 (45.83%)
Abdominal pain scoreb [1–10]
   2 6 6 (5.77%) 0 (0.00%) 0.142 0.707
   3 9 7 (6.73%) 2 (8.33%)
   4 15 12 (11.54%) 3 (12.50%)
   5 21 15 (14.56%) 5 (20.83%)
   6 1 1 (0.96%) 0 (0.00%)
   7 37 31 (29.81%) 6 (25.00%)
   8 16 13 (12.50%) 3 (12.50%)
   9 19 16 (15.38%) 3 (12.50%)
   10 4 2 (1.94%) 2 (8.33%)
Nausea and vomiting score [0–2]
   0 31 24 (23.08%) 7 (29.17%) 1.671 0.196
   1 65 59 (57.28%) 6 (25.00%)
   2 31 20 (19.23%) 11 (45.83%)
Abdominal pain type [1–3]
   1 101 80 (77.67%) 20 (83.33%) 0.385 0.535
   2 25 21 (20.19%) 4 (16.67%)
   3 2 2 (1.94%) 0 (0.00%)
Abdominal tenderness range [1–10]
   1 25 20 (19.23%) 5 (20.83%) 1.738 0.187
   2 18 15 (14.56%) 3 (12.50%)
   3 49 43 (41.75%) 5 (20.83%)
   4 5 3 (2.91%) 2 (8.33%)
   5 1 1 (0.97%) 0 (0.00%)
   6 1 1 (0.97%) 0 (0.00%)
   7 2 2 (1.94%) 0 (0.00%)
   8 5 5 (4.85%) 0 (0.00%)
   9 22 13 (12.62%) 9 (37.50%)
Abdominal pain time (hours, mean ± SD) 127 23.80±14.90 36.00±14.26 −3.641 <0.001*
Highest temperature (°C, mean ± SD) 127 37.46±0.80 38.04±0.94 −3.094 0.002*
WBC counts (×109) (mean ± SD) 127 13.73±4.23 15.26±3.33 −1.656 0.1
NE% (mean ± SD) 127 85.03±7.02 87.09±4.63 −1.76 0.084
CD3+ (%, mean ± SD) 127 65.47±8.52 64.37±12.17 0.525 0.6
CD4+ (%, mean ± SD) 127 34.21±7.98 31.70±7.23 1.409 0.161
CD8+ (%, mean ± SD) 127 27.16±8.20 34.71±10.67 −3.83 <0.001*
CD19+ (%, mean ± SD) 127 17.53±7.50 17.98±7.37 -0.263 0.793
CD16+56- (%, mean ± SD) 127 15.32±8.54 13.72±9.36 0.813 0.418
Total T cell counts (µL, mean ± SD) 127 880.42±494.62 835.49±418.38 0.412 0.681
Helper T cell counts (µL, mean ± SD) 127 469.24±281.09 396.50±213.86 1.189 0.237
Inhibitor T (µL, mean ± SD) 127 358.03±220.44 396.88±252.29 −0.756 0.451
B cell counts (µL, mean ± SD) 127 224.89±130.69 203.17±90.04 0.772 0.442
NK cell counts (L, mean ± SD) 127 199.96±150.11 166.75±97.37 1.033 0.304
CD4+/CD8+ (mean ± SD) 127 1.45±0.71 1.22±0.65 1.423 0.157
CRP, mg/L (mean ± SD) 127 52.10±51.72 103.85±72.48 −4.068 <0.001*
PCT, ng/L (mean ± SD) 127 1.44±4.70 4.46±9.21 −1.559 0.131

P value <0.05 indicated statistical significance. * indicated statistical significance. aFisher’s exact test was used for the nominal variable. Wilcoxon test was used for the ordinal variable, whose statistics is W. Student’s t test was used for the continuous variable with abnormal distribution, whose statistics is t. bIt is same to Table 1. SD, standard deviation; WBC, white blood cell; NE, neutrophil; PCT, procalcitonin; hs-CRP, high-sensitivity C-reactive protein.