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CircHIPK3 regulates the expression of NUPR1/PI3K/AKT by sponging miR-637. (A,B,C) QRT-PCR is used to detect expressions of circHIPK3, miR-637, and NUPR1 mRNA in Tca8113 cells transfected with circHIPK3 overexpression plasmid or miR-637 mimic. ***P<0.001; (D,E) Western blot is used to detect expressions of NUPR1 and PI3K/AKT. ***P<0.001. circHIPK3, circular RNA HIPK3; miR-637, microRNA-637; NUPR1, Nucleoprotein 1; QRT-PCR, quantitative real-time PCR.
