Figure 1.

Proof-of-Principle Metabolic Images Acquired From the Ischemic Heart Using Hyperpolarized ¹³C CMR

(A) Schematic representation of metabolic pathways observable following injection of hyperpolarized [1-¹³C]pyruvate. (B and C) Representative late gadolinium/metabolic images acquired from Subject #1. (D and E) Representative late gadolinium/metabolic images acquired from Subject #2. CMR = cardiac magnetic resonance; HSS = hybrid-shot spiral; LDH = lactate dehydrogenase; PDH = pyruvate dehydrogenase.