Figure 6.

Gap junction blockers reduce neuronal cascade intensity

(A) Representative stack summation of binary time series from stxbp1b mutants before (top row) and after (bottom row) heptanol treatment. The cumulative intensity of activation is color coded as shown in the color bar.

(B) Comparison of normalized (norm.) number (num) of cascade, maximum (max) cascade size, and maximum cascade duration (dur) before and after heptanol treatment. Data were normalized to the average value from recordings before drug treatment. (C and D) Results from propofol experiments on stxbp1b mutants. Scale bars, 100 μm. n = 5 fish for each drug test. Statistical significance is indicated as ∗p < 0.05, ∗∗p < 0.01; Student's t test.