Table 3.
Inpatient alerts, inpatient genetic alerts, and outpatient alerts
| Cohort | The Seegnal platform | EPIC (control group) | p value |
|---|---|---|---|
| Inpatient | |||
| Number of patients | 657 | 657 | NA |
| Number of admissions | 665 | 665 | NA |
| Interruptive alerts | 1697 | 27,540 | NA |
| Alert load | 6% | 100% | NA |
| True positives | 1422 | 979 | NA |
| False positives | 275 | 26,561 | NA |
| True negatives | 26,359 | 72 | NA |
| False negatives | 0 | 444 | NA |
| PPV | 83.81% | 3.55% | < 0.0001 |
| NPV | 100% | 14.01% | < 0.0001 |
| Sensitivity | 100% | 68.8% | < 0.0001 |
| Specificity | 99% | 0.3% | < 0.0001 |
| Inpatient genetic | |||
| Number of patients | 413 | 413 | NA |
| Number of admissions | 413 | 413 | NA |
| Interruptive alerts | 1493 | 20,975 | NA |
| Alert load | 7% | 100% | NA |
| True positives | 1068 | 1034 | NA |
| False positives | 425 | 19,941 | NA |
| True negatives | 19,748 | 232 | NA |
| False negatives | 250 | 284 | NA |
| PPV | 71.51% | 4.93% | < 0.0001 |
| NPV | 99% | 44.98% | < 0.0001 |
| Sensitivity | 81% | 78.5% | 0.11 |
| Specificity | 97.9% | 1.2% | < 0.0001 |
| Outpatient | |||
| Number of patients | 2731 | 2731 | NA |
| Number of admissions | 2749 | 2749 | NA |
| Interruptive alerts | 2341 | 35,134 | NA |
| Alert load | 7% | 100% | NA |
| True positives | 1924 | 1700 | NA |
| False positives | 407 | 33,424 | NA |
| True negatives | 33,134 | 117 | NA |
| False negatives | 248 | 472 | NA |
| PPV | 82.54% | 4.84% | < 0.0001 |
| NPV | 99% | 19.84% | < 0.0001 |
| Sensitivity | 88.6% | 78.3% | < 0.0001 |
| Specificity | 99% | 0.3% | < 0.0001 |
NA not applicable, NPV negative predictive value, PPV positive predictive value