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. 2020 Nov 10;73(3):1081–1091. doi: 10.1007/s13304-020-00911-6

Table 4.

Univariate analysis and multivariate Cox regression analysis for OS and DFS

Univariate analysis Multivariate analysis
Variable 5-year OS (%) p 5-year DFS (%) p 5-year OS 5-year DFS
OR 95% CI p OR 95% CI p
Age, ≥ 65/ < 65 83/96 0.1 80.6/85.1 0.92
Sex, M/F 89.2/93.3 0.26 85.5/82.3 0.85
ASA, I–II/III–IV 100/89.2 0.33 85/69.6 0.37
BMI, < 25/ ≥ 25 95.5/80.8 0.6 87.8/76.4 0.57
Tumor location, high-middle/low 91.4/87.6 0.5 85/77.5 0.47
Neadjuvant treatment, yes/no 92.8/88.8 0.7 80.1/87.9 0.35
Type of surgery, ARR/APR 91.5/85.7 0.77 82.9/85.7 0.48
Diverting ostomy, yes/no 86.3/95 0.1 80/87.9 0.35
Conversion, yes/no 90/100 0.5 80/83.6 0.42
Complications, yes/no 96.3/88.5 0.78 75.9/86 0.21
Reoperation, yes/no 90.5/100 0.73 83/100 0.61
TNM stage, I–II/III 96.1/71.6 0.04 94.6/51.6  < 0.0001 0.1 –0.3 to 0.6 0.47 1.2 0.47–2 0.02
Lymph nodes harvesteda, ≤ 11/ > 11 92.6/86.6 0.3 83.5/82.4 0.23
CRM, positive/negative 33/95.7  < 0.0001 33.3/88  < 0.0001 7.6 6.3–9  < 0.0001 3.7 1.4–6.1 0.02

TME quality,

complete/near complete-incomplete

98/21.4  < 0.0001 93.3/14.3  < 0.0001 1.8 1.34–2.25  < 0.0001 3.9 3.1–4.7  < 0.0001

aThe mean values of lymph nodes harvested was used for the univariate and multivariate analysis

OS overall survival, DFS disease-free survival, OR odds ratio, CI confidence interval