Table 1.

The binding constants, K_H:G, determined through UV-Vis titration and Os-reaction scheme for the threo and erythro diols.

Set	trans-alkene	cis-alkene	threo diol	erythro diol
1: R1, R2 = CH3	G1T	G1C	G1TH	G1ER
KH:G[a]	—	—	0.348	0.057
2: R1, R2 = Ph	G2T	G2C	G2TH	G2ER
KH:G[a]	—	—	11.1	[b]
3: R1 = (CH2)7CH3 R2 = (CH2)7COOCH3	G3T	G3C	G3TH	G3ER
KH:G[a]	—	—	1.38	[b]
4: R1, R2 = (CH2)2CH3	G4T	G4C	G4TH	G4ER
KH:G[a]	—	—	1.10	0.16
5: R1 = CH3 R2 = (CH2)2CH3	G5T	G5C	G5TH	G5ER
KH:G[a]	—	—	2.64[c]	0.29[c]
6: R1, R2 = CH(CH3)2	G6T	G6C	G6TH	G6ER
KH:G[a]	—	—	3.72	[b]
7:
	G7T	G7C	G7TH	G7ER
KH:G[a]	—	—	1.41[c]	0.41 [c]

^[a]10³ M⁻¹

^[b]negligible measurement

^[c]binding constants determined using the 96-well plate, see supplementary information.