FIGURE 1.

mRNA and protein expression of xCT in gastric cancer clinical samples and gastric cancer cell lines. A, The upper panel demonstrates the HE staining of normal and tumour tissues at 100× and 200× magnification. The lower panel demonstrates the immunochemical staining of the expression of xCT in gastric cancer tissues and normal gastric cancer tissues at 100× and 200× magnification. B, qPCR demonstrated the relative expression of xCT in eight paired gastric cancer and normal gastric tissues. C, The protein expression of xCT in eight gastric cancer specimens and paired corresponding normal gastric tissues. D, The protein expression of xCT in eight gastric cancer cell lines and normal gastric cells. E, The mRNA expression of xCT in tumour and normal gastric tissues based on data from the TCGA database. F, Survival analysis demonstrated that higher expression of xCT is associated with poor overall survival (P < .05)