FIGURE 2.

Bioinformatics analysis of KLF15‐binding genes. A, DAVID analysis and IPA were performed to acquire the GO domains of the 1,357 SILAC‐LC/MS‐screened proteins. B, Top 30 signalling pathways identified by IPA of the SILAC‐LC/MS data. C, Fifty‐two genes identified by bioinformatics analysis of ChIP‐Seq data and SILAC‐LC/MS data. D, KLF15 and SUMO1 mRNA expression in HG‐treated HRMCs. E, KLF15 and SUMO1 mRNA expression in PDGF‐BB‐treated HRMCs. F‐G, KLF15 and SUMO1 protein expression in HG‐treated HRMCs. H‐I, KLF15 and SUMO1 protein expression in PDGF‐BB‐treated HRMCs. *P < .05, ***P < .01, n = 3