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. 2021 May 4;25(12):5691–5706. doi: 10.1111/jcmm.16583

FIGURE 5.

FIGURE 5

Both KLF15 overexpression and SUMO1 overexpression inhibit PDGF‐BB‐induced cell proliferation. A‐C, HRMCs were transfected with a control plasmid (VECTOR) or a KLF15 overexpression plasmid (KLF15) and incubated with PDGF‐BB. A, The expression of SUMO1‐P53 and input (P53) was assessed by IP analysis. B, The expression of KLF15 and SUMO1 was assessed by Western blot analysis. C, Quantitative data. D‐F, HRMCs were transfected with an empty vector (VECTOR) or a SUMO1 overexpression plasmid (SUMO1) and incubated with PDGF‐BB. D, The expression of SUMO1‐P53 and input (P53) was assessed by IP analysis. E, The expression of KLF15 and SUMO1 was assessed by Western blot analysis. F, Quantitative data. G‐H, Cell proliferation assay results. KLF15 or SUMO1 overexpression inhibited PDGF‐BB‐induced cell proliferation. *P < .05, n = 3