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Schematic presentation of the mechanism of wogonin to alleviate septic liver injury. Wogonin treatment activated Nrf2 signalling, promoted transcription and expression of endogenous antioxidants including NQO‐1, GST, HO‐1, SOD which suppressed sepsis‐induced oxidative stress in hepatocytes. Moreover, wogonin‐promoted Nrf2 signalling inhibited NF‐κB activation and decreased production of pro‐inflammatory cytokines, which mitigated inflammatory damage of hepatocytes in sepsis
