TABLE 1.
KEGG pathways most significantly enriched with up‐regulated SCGs
| Pathway | KEGG ID | P | BH.adj.P | Genes in pathway | SCGs in pathway | Gene symbols of SCGs in pathway |
|---|---|---|---|---|---|---|
| Retinol metabolism | hsa00830 | 1.62 × 10−7 | 4.6 × 10−6 | 24 | 7 | ALDH1A3, BCO1, LRAT, RDH10, RDH11, RDH5, RPE65 |
| Cytokine‐cytokine receptor interaction | hsa04060 | .000298 | .00783 | 113 | 10 | ACVR1C, BMP4, BMP6, BMP7, BMP8B, CXCR2, GDF11, IL16, IL17RB, TNFRSF10C |
| Ether lipid metabolism | hsa00565 | .00078 | .0166 | 27 | 4 | ENPP2, PLA2G5, PLA2G7, SELENOI |
| Gastric acid secretion | hsa04971 | .00303 | .0517 | 52 | 5 | CAMK2B, HRH2, PRKCB, SLC26A7, SLC4A2 |
| Glycerophospholipid metabolism | hsa00564 | .00346 | .0561 | 71 | 6 | GPAM, GPD1, PCYT1B, PLA1A, PLA2G5, SELENOI |
| Cysteine and methionine metabolism | hsa00270 | .00424 | .0628 | 39 | 4 | BCAT1, CDO1, CTH, GOT2 |
| Bile secretion | hsa04976 | .00527 | .0691 | 41 | 4 | SLC22A8, SLC4A2, SLC4A5, SLCO1A2 |
| Mineral absorption | hsa04978 | .00527 | .0691 | 41 | 4 | ATP2B2, CLCN2, TRPM6, TRPM7 |