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. 2021 May 13;25(12):5753–5768. doi: 10.1111/jcmm.16599

FIGURE 2.

FIGURE 2

QLX exerts protective effect in hormonal imbalance–induced CNP and BPH. A, Representative photographs showing the size of prostate glands. B, The prostate index was based on the weight of prostate relative to the rat bodyweight. C, Representative HE staining of prostate tissue showing D, the thickness of the epithelium and E, the luminal area. Castrated rats were treated with oestradiol or testosterone to induce CNP and BPH. Black frame in the middle panel indicates the luminal area. Black frame in the lower panel indicates the thickness of the epithelium. The typical enlarged photographs are shown in the lower panel as indicated. QLX was administered at the indicated dose for 45 days. Tamsulosin was used as a positive control. Control rats were treated by sham surgery. Data are means ± SD, n = 6. # P < .05, ## P < .01 (sham vs. oestradiol or testosterone‐treated rats); * P < .05, ** P <.01 (QLX‐treated vs. oestradiol or testosterone‐treated rats); $$ P < .01 (tamsulosin‐treated vs oestradiol or testosterone‐treated rats); & P < .05 (tamsulosin‐treated vs. QLX‐treated rats)