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. 2021 Jun 7;12:3361. doi: 10.1038/s41467-021-23695-8

Table 1.

Comparison between FISH diagnoses and FFPE-TLC results.

MYC FFPE-TLC
MYC-IGH MYC-IGL MYC-IGK MYC-others MYC negative
Control Negative (n = 20) 0 0 0 0 20
BCL2 BCL2-IGH BCL2-IGL BCL2-IGK BCL2-others BCL2 negative
Negative (n = 20) 0 0 0 0 20
BCL6 BCL6-IGH BCL6-IGL BCL6-IGK BCL6-others BCL6 negative
Negative (n = 20) 0 0 0 0 20
MYC FFPE-TLC
MYC-IGH MYC-IGL MYC-IGK MYC-others MYC negative
FISH Positive (n = 49) 30 4 1 12 2
Negative (n = 75) 0 0 0 2 73
Inconclusive (n = 1) 0 0 0 0 1
No data (n = 24) 0 0 0 0 24
BCL2 FFPE-TLC
BCL2-IGH BCL2-IGL BCL2-IGK BCL2-others BCL2 negative
FISH Positive (n = 31) 30 0 1 0 0
Negative (n = 63) 0 0 0 0 63
Inconclusive (n = 3) 0 0 0 0 3
No data (n = 52) 3 0 0 0 49
BCL6 FFPE-TLC
BCL6-IGH BCL6-IGL BCL6-IGK BCL6-others BCL6 negative
FISH Positive (n = 29) 12 3 0 14 0
Negative (n = 61) 2 0 0 1 58
Inconclusive (n = 3) 1 0 0 1 1
No data (n = 56) 2 2 0 2 50

Quantitative overview of samples with FISH diagnosis horizontally and FFPE-TLC calls (using PLIER) vertically. Note that ‘inconclusive’ FISH results refer to samples carrying an unusual or uneven number of FISH signals.