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. 2021 Jun 7;12:3367. doi: 10.1038/s41467-021-23637-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Compositions of DMRs among TEs, genes, and intergenic regions (IGs). DMRs (relative to the WT) were identified in rdm15, nrpd1-3, and nrpe1-11. b Box plots showing CG, CHG, and CHH methylation levels of rdm15 DMRs in Col-0, rdm15-2, rdm15-3, and nrpd1-3. Data from two replicates are shown. c Venn diagram showing the numbers of hypomethylated DMRs that overlapped between rdm15, nrpd1-3, and nrpe1-11. d The Integrative Genome Browser (IGB) display of whole-genome bisulfite sequencing (WGBS) data is shown for several representative rdm15 DMRs in Col-0, rdm15-2, rdm15-3, and nrpd1-3. Vertical bars on each track indicate DNA methylation levels. The coordinates of DMRs are indicated below the snapshots. Two replicates are shown for each genotype.