Table 2.
Ingenuity pathway analysis® of the genes regulated upon FBXO32 silencing.
| Diseases or functions annotation | p-value | z-score | Molecules |
|---|---|---|---|
| Proliferation of cells | 3.39E–04 | –3.66 | 104 |
| Neoplasia of epithelial tissue | 2.71E–04 | –2.56 | 243 |
| Cell proliferation of tumor cell lines | 3.71E–03 | –2.50 | 49 |
| Cell proliferation of breast cancer cells | 8.20E–03 | –2.39 | 17 |
| Epithelial cancer | 4.34E–04 | –2.36 | 241 |
| Formation of cellular protrusions | 7.73E–03 | –2.35 | 28 |
| Apoptosis of blood cells | 5.98E–03 | –2.27 | 18 |
| Development of neurons | 3.00E–04 | –2.17 | 31 |
| Invasion of tumor cell lines | 6.19E–03 | –2.16 | 24 |
| Neuritogenesis | 3.19E–04 | –2.01 | 25 |