Table 1.

Univariate and multivariate Cox regression analyses for overall survival in PCa patients enrolled in tissue microarray.

	Univariable models		Multivariable models		Multivariable models
Variables	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Age (years)
≤65	Ref.		Ref.		Ref.
>65	11.60 (1.55, 86.75)	0.017	14.11 (1.67, 119.22)	0.015	13.31 (1.63, 108.51)	<0.001
Gleason grade group at RP			–		–
1	Ref.
2	0.49 (0.04, 5.44)	0.563
≥3	2.35 (0.31, 17.67)	0.408
Pathological T stage					–
T2	Ref.		Ref.
T3a	4.36 (1.47, 12.95)	0.008	0.79 (0.20, 3.10)	0.730
T3b	9.17 (2.49, 33.86)	0.001	0.78 (0.16, 3.83)	0.758
Pathological N stage
N0	Ref.		Ref.		Ref.
N1	14.27 (4.74, 42.95)	<0.001	34.48 (6.67, 178.34)	<0.001	28.32 (7.89, 101.60)	<0.001
IRS of HJURP
≤6	Ref.		Ref.		Ref.
>6	6.63 (1.94, 22.64)	0.003	5.84 (1.56, 21.85)	0.009	5.62 (1.53, 20.60)	0.009
Surgical margins
Negative	Ref.		Ref.		Ref.
Positive	6.01 (2.44, 14.84)	<0.001	11.12 (3.60, 34.31)	<0.001	10.38 (3.55, 30.42)	<0.001

IRS immunoreactivity score, RP radical prostatectomy.