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. 2021 Mar 23;124(12):1912–1920. doi: 10.1038/s41416-021-01329-6

Fig. 3. Other cells in the bone metastatic niche.

Fig. 3

Other cells in the bone niches include immune cells in the bone marrow (dendritic cells, macrophages, myeloid-derived suppressor cells (MDSCs), natural killer (NK) cells, T cells and megakaryocytes), adipocytes and sympathetic nerve cells. These bone stromal cells regulate the immune escape, dormancy and proliferation abilities of tumour cells.