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. 2021 Jun 7;11:11949. doi: 10.1038/s41598-021-90570-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A) ALDH expression was evaluated in the PanCancer Atlas. An OncoPrint depicts the results and shows the graphical summary of mRNA alternations in all 19 ALDH isoforms across a set of 527 endometrial tumor samples (TCGA, PanCancer Atlas). (B) Distribution of ALDH isoforms in serous/papillary, mixed or endometrioid endometrial cancer. (C) Kaplan–Meier plot showing overall survival of Endometrial Carcinoma patients from the TCGA database with altered (red, number of patients, n = 299) or unaltered ALDH expression (blue, number of patients, n = 228). The Two-sided log-rank P value is displayed. (C) Kaplan–Meier plot showing overall survival of Endometrial Carcinoma patients from the TCGA database with altered (red; number of patients, n = 115) or unaltered ALDH1 expression (blue, number of patients, n = 412). A two-sided log-rank P value is displayed.