Table 1.
Clinical variables and patient groups stratified based on cytoplasmic ALDH1 expression.
| All patients | ALDH1 negative (% of total) | ALDH1 positive (% of total) | p value | |
|---|---|---|---|---|
| Total | 158 | 105 (66%) | 53 (34%) | |
| BMI (kg/m2) | ||||
| Median (range) | 27 (16–57) | 27 (16–56) | 28 (20–57) | 0.13a |
| Mean | 29 | 28 | 30 | |
| BMI < 30 | 83 (60%) | 56 (40%) | 27 (19%) | 0.72b |
| BMI ≥ 30 | 56 (40%) | 36 (26%) | 20 (14%) | |
| Ethnicity | ||||
| Others | 28 (19%) | 17 (11%) | 11 (7%) | 0.50b |
| Caucasian | 122 (81%) | 84 (56%) | 38 (25%) | |
| Age of 1st biopsy (years) | ||||
| Median (range) | 46 (24–83) | 46 (24–74) | 47 (29–83) | 0.87a |
| Mean | 47 | 47 | 47 | |
| Age of EC diagnosis (years) | ||||
| Median (range) | 56 (30–86) | 60 (30–79) | 55 (35–86) | 0.31a |
| Mean | 57 | 58 | 55 | |
| Number of women | 41 | 23 | 18 | |
| Follow-up time (months) | ||||
| Mean | 64 | 72 | 49 | 0.01a |
| Median (range) | 54 (0–249) | 55 (0–249) | 45 (0–176) | |
| Smoking history | ||||
| Yes | 50 (35%) | 32 (22%) | 18 (13%) | 0.86b |
| No | 94 (65%) | 62 (43%) | 32 (22%) | |
| Gravidity | ||||
| Median (range) | 2 (0–8) | 2 (0–8) | 2 (0–6) | 0.80b |
| Parity | ||||
| Median (range) | 1 (0–6) | 1 (0–6) | 1 (0–4) | 0.81b |
| 0–1 | 78 (53%) | 48 (33%) | 30 (21%) | |
| ≥ 2 | 68 (47%) | 47 (32%) | 21 (14%) | |
| Menopause (years) | ||||
| Median (range) | 50 (31–59) | 50 (31–59) | 50 (34–56) | 0.69a |
| Mean | 49 | 49 | 49 | |
| < 48 years | 38 (27%) | 24 (17%) | 14 (30%) | |
| 48–52 years | 71 (51%) | 49 (35%) | 22 (16%) | |
| > 52 years | 31 (22%) | 21 (15%) | 10 (7%) | |
| Diabetes mellitus | ||||
| No | 113 (80%) | 75 (53%) | 38 (27%) | 0.67b |
| Yes | 29 (20%) | 18 (13%) | 11 (8%) | |
| Estrogen therapy history | ||||
| Yes | 82 (53%) | 57 (37%) | 25 (16%) | 0.61b |
| No | 73 (47%) | 47 (30%) | 26 (17%) | |
| Progesterone therapy history | ||||
| Yes | 109 (70%) | 73 (47%) | 36 (23%) | 1b |
| No | 46 (30%) | 31 (20%) | 15 (10%) | |
aMann–Whitney.
bFisher's Exact.