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. 2021 May 25;9:635503. doi: 10.3389/fped.2021.635503

Table 2.

Anthropometric, atopic, and lung function data at 11 years of the study population.

Term controls (N = 55) All preterms (n = 55) PRETERMS NO BPD (N = 50) Preterms with BPD (N = 5) P-values terms vs. preterms P-values BPD vs. no BPD P-values terms vs. no BPD
Anthropometric data
Age (years) 11.1 ± 0.9 11.0 ± 0.6 11.0 ± 0.6 11.1 ± 0.8 0.81 0.86 0.77
Weight (kg) 43.3 ± 9.7 42.3 ± 10.0 42.4 ± 9.9 41.6 ± 11.9 0.64 0.82 0.81
Height (cm) 148.2 ± 10.7 145.3 ± 8.1 145.3 ± 8.3 145.2 ± 6.6 0.49 0.95 0.50
BMI (kg/m2) 19.6 ± 3.1 19.8 ± 3.4 19.8 ± 3.4 19.5 ± 3.9 0.71 0.77 0.65
Atopic characteristics
EO% 3.1 ± 2.0 3.5 ± 2.5 3.2 ± 2.2 5.1 ± 3.7 0.61 0.36 0.86
SPT positive 32.7% 38.2% 36.0% 60.0% 0.69 0.35 0.83
FeNO (ppb) 10.8 ± 4.1 10.7 ± 5.3 10.4 ± 4.8 14.6 ± 9.5 0.45 0.31 0.39
Lung function
FEV1 Z-score 0.7 ± 0.9 0.5 ± 1.3 0.6 ± 1.3 0.1 ± 1.1 0.49 0.34 0.74
FVC Z-score 0.2 ± 0.6 0.2 ± 1.2 0.2 ± 1.2 −0.1 ± 1.1 0.94 0.41 0.91
FEV1/FVC Z-score 0.7 ± 0.9 0.6 ± 1.0 0.6 ± 1.1 0.4 ± 0.6 0.72 0.62 0.79
FEF75 Z-score 1.3 ± 0.8 1.2 ± 1.1 1.3 ± 1.0 0.6 ± 0.5 0.33 0.09 0.82
FEF25−75 Z-score 0.5 ± 0.7 0.3 ± 0.9 0.3 ± 0.9 −0.1 ± 0.5 0.16 0.16 0.31
sRaw% 169.2 ± 24.9 187.7 ± 48.1 184.4 ± 48.9 219.6 ± 23.4 0.04 0.02 0.16
VR% 106.9 ± 32.6 105.9 ± 54.4 106.2 ± 56.9 103.2 ± 23.3 0.22 0.48 0.19
TLC% 103.9 ± 16.1 98.5 ± 14.9 98.5 ± 15.6 98.4 ± 4.0 0.02 0.33 0.01
Bronchoreversibility 3.6% 9.1% 8.0% 20.0% 0.44 0.39 0.42

Values are percentages for categorical data and mean ± standard deviation for continuous variables.

BPD, bronchopulmonary dysplasia; BMI, body mass index; EO%, serum eosinophils; SPT, skin prick test; FeNO, fractional exhaled nitric oxide; DLCO, carbon monoxide diffusing capacity; FEV1, forced expiratory volume in the 1st second; FVC, forced vital capacity; FEF75, forced expiratory flow at 75% of FVC; FEF25−75, forced expiratory flow between 25 and 75% of FVC; sRaw, specific airway resistance; VR, residual volume; TLC, total lung capacity.

The statistical significance level is p < 0.05 and it is indicated in bold.