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. 2021 Jun 7;9:30. doi: 10.1038/s41413-021-00148-y

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© The Author(s) 2021, corrected publication 2021

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Fig. 2 — Nsd1 deficiency in mesenchymal progenitors led to skeletal growth defects in mice. Gross images of 1-month-old WT, Nsd1^f/f;Prx1-Cre (a) and Nsd1^f/f;Col2-Cre (b) mice. Pictures of hindlimbs (left) and quantitative statistics (right) of hindlimb length in 1-month-old WT, Nsd1^f/f;Prx1-Cre (c) and Nsd1^f/f;Col2-Cre (d) mice. Scale bar = 2 mm. The values are presented as the means ± SEMs, n = 6. *P < 0.05, ns means not significant. Safranin O (SO) staining results (e, g) and growth plate quantification data (f, h) of tibia sections from 1-month-old WT, Nsd1^f/f;Prx1-Cre (e, f) and Nsd1^f/f;Col2-Cre (g, h) mice. Scale bar (top) = 100 μm. Scale bar (bottom) = 50 μm. The values are presented as the means ± SEMs, n = 6. *P < 0.05, **P < 0.01, ns means not significant