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. 2021 Apr 7;124(12):1949–1958. doi: 10.1038/s41416-021-01367-0

Table 1.

The comprehensive geriatric assessment, results and interventions.

Domain Assessment and screening tool Possible interventions Interventions implemented
Cut-off Score n (%) n (%)
Comorbidity CIRS-G

0–4

5–7

11 (15)

31 (44)

Optimising treatment Referrals to exams/other departments Referrals 23 (32)
Review of medical records ≥8 29 (41)
Clinical examination
Patient interview
Medication review No. of medications/polypharmacy 0–4 43 (61) Discontinuation Changes in medication 44 (62)
≥5 28 (39) Prescription
START/STOP criteria Change in dosage
Cognitive function MMSE  ≤23/30 24–30 71 (100) Further evaluation Cognitive evaluation 1 (1.4)
0–23 0 (0) Referral/medication
Psychological function GDS  ≥ 6/ 15 0–5 67 (9) Assessment of possible depression Medical treatment 2 (2.8)
≥6 4 (6) Referrals 2 (2.8)
Nutritional status MNA-based local nutritional screening Weight loss ≥5% 0–5 18 (25) Nutritional supplements Referral: GERICO dietitian 36 (51)
≥5 53 (75) Referral to dietitiana
Physical function Gait speed 10 m >1 m/s 0–1 37 (52) Referral to the exercise programmeb Referral: GERICO exercise programme 28 (39)
>1 32 (45)
Handgrip strength (Jamar Dynamometer) <♀ 20 kg below 35 (49) Referral to the exercise training programmeb Referral: GERICO exercise programme 28 (39)
<♂ 30 kg above 36 (51)
Functional status Katz ADL <6 6 62 (87) Initiation of home care Initiation of social support 2 (2.8)
(In)dependence 0–5.5 9 (13) Occupational therapy assessment Occupational therapy 2 (2.8)
FAQ IADL >1 0 48 (68) Initiation of home care Initiation of home care 2 (2.8)
(In)dependence ≥1 23 (32) Transport arrangement
Laboratory parameters TSH, cobalamin, folate, albumin, vitamin D Normative values Normal 51 (72) Treat deficiencies/control blood samples Deficiencies treated 20 (28)
abnormal 20 (28)

ADL activities of daily living, CIRS-G Critical Illness Rating Score—Geriatrics, FAQ IADL frequently asked questions instrumental activities of daily living, GDS Geriatric Depression Scale, MMSE minimal mental state examination, MNA minimal nutritional assessment.

aA personalised nutritional plan based on the patient’s taste preferences and a telephone follow-up call after 1 month, and 3 months after chemotherapy discontinuation.

bThe exercise programme included 24 supervised exercise sessions preferably twice weekly at the hospital and home exercise once weekly. The supervised exercise was a 1-h training programme including 15 min of warming up with aerobic and balance training, 30 min of resistance training, and finally 15 min of supervised relaxation.