Table 4.
Multiple comparison of quantitative effects of the different treatment vs. untreated wounds.
| Parameter (p-value) | Treatment | N | Mean ± SD | Significant Comparisons | P*-value |
|---|---|---|---|---|---|
| Final microbiological count (Log10) (NS) |
aPDT aPDT + MU MU Control |
52 56 36 55 |
1.464 ± 1.740 0.950 ± 1.552 0.677 ± 1.346 1.711 ± 2.124 |
MU vs. aPDT aPDT+MU vs. control MU vs. control |
0.0250 0.0332 0.0110 |
| Size (cm) (< 0.0001) |
aPDT aPDT + MU MU Control |
52 56 36 55 |
0.208 ± 0.113 0.371 ± 0.169 0.328 ± 0.145 0.430 ± 0.105 |
aPDT vs. aPDT+MU aPDT vs. MU aPDT + MU vs. control aPDT vs. control MU vs. control |
< 0.0001 < 0.0001 0.0287 < 0.0001 0.0002 |
| Crust loss (days) (< 0.0001) |
aPDT aPDT + MU MU Control |
52 56 36 78 |
4.692 ± 0.701 5.643 ± 1.069 5.944 ± 1.241 5.167 ± 1.074 |
aPDT vs. aPDT + MU aPDT vs. MU aPDT+MU vs. control aPDT vs. control MU vs. control |
< 0.0001 < 0.0001 0.0124 0.0058 0.0009 |
| Size reduction 50% (days) (< 0.0001) |
aPDT aPDT + MU MU Control |
52 56 36 78 |
5.327 ± 0.706 7.125 ± 1.466 8.472 ± 2.569 10.667 ± 1.898 |
aPDT vs. aPDT+MU MU vs. aPDT + MU aPDT vs. MU aPDT + MU vs. control aPDT vs. control MU vs. control |
< 0.0001 0.0019 < 0.0001 < 0.0001 < 0.0001 < 0.0001 |
*
Kruskal Wallis (p significative). aPDT, antimicrobial photodynamic therapy; MU, mupirocin.