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. 2021 Jun 3;14:3583–3596. doi: 10.2147/OTT.S302028

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© 2021 Huang et al.

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ITGA2 overexpression promotes ESCC cells aggressiveness.(A–E) ITGA2 was stably overexpressed in ECA-109 cells. Flow cytometry analysis of apoptosis (A), CCK8 assay (B), colony formation assay (C), wound healing assay (D), invasion and migration assay (E and F). For (E and F), displayed invasion and migration images are based on Transwell assays. The high expression ITGA2 group was compared to the Vector group. Each barsshowthe mean±SD of 3 independent experiments. Data were statistically analyzed with paired two-tailed students, t-test. *p<0.05; **p<0.01; ***p<0.001.