Table 2.
Single-nucleotide polymorphisms (SNPs) used to define blood antigen phenotypes of participants in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
| Blood type | Chromosome:position | SNP [63–66] | Nucleotide | Weighted prevalence (%) |
|---|---|---|---|---|
| ABO | ||||
| A1 | Ref | Ref | Ref | 11.5 |
| A2 | 9:133256264 | rs1053878 | A | 7.9 |
| B | 9:133256205/133257486 | rs7853989/rs8176720 | G/G | 17.3 |
| O (null) | 9:133257521-133257522 | rs8176719 | Del | 63.3 |
| Auburger | ||||
| A | Ref | Ref | Ref | 66.4 |
| B | 19:44819487 | rs1135062 | G | 33.6 |
| Colton | ||||
| A | Ref | Ref | Ref | 96.4 |
| B | 7:30912043 | rs28362692 | T | 3.6 |
| Dombrock | ||||
| A | Ref | Ref | Ref | 69.8 |
| B | 12:14840505 | rs11276 | T | 30.2 |
| Duffy | ||||
| A | Ref | Ref | Ref | 57.4 |
| B | 1:159205564 | rs12075 | A | 40.8 |
| x | 1:159205704 | rs34599082 | T | 1.8 |
| Null | 1:159204893 | rs2814778 | C | <0.1 |
| Kell | ||||
| k | Ref | Ref | Ref | 94.7 |
| K | 7:142957921 | rs8176058 | A | 5.3 |
| Kidd | ||||
| A | Ref | Ref | Ref | 49.8 |
| B | 18:45739554 | rs1058396 | A | 50.2 |
| Knops | ||||
| A | Ref | Ref | Ref | 97.4 |
| B | 1:207609424 | rs41274768 | G | 2.6 |
| Lewis | ||||
| A | Ref | Ref | Ref | 32.1 |
| le1 (Null) | 19:5844781/5844332 | rs28362459/rs3745635 | C/T | 6.5 |
| le2 (Null) | 19:5844781/5843773 | rs28362459/rs3894326 | C/T | 3.4 |
| B | 19:48703417 | rs601338 | G | 58 |
| Lutheran | ||||
| A | Ref | Ref | Ref | 96.5 |
| B | 19:44812188 | rs28399653 | G | 3.5 |
| RhE | ||||
| E | Ref | Ref | Ref | 86.1 |
| e | 1:25390874 | rs609320 | G | 13.9 |
| Secretor | ||||
| Se | Ref | Ref | Ref | 58 |
| se (null) | 19:48703417 | rs601338 | A | 42 |