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. 2021 May 25;11:664421. doi: 10.3389/fonc.2021.664421

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Copyright © 2021 Zhang, Li, Lou, Chen, Yu, Kang, Chen, Zhou, Zong, Yang, Li, Xu, Jia, Geng, Chen, Dai, Tang, Yu, Wu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between cellular kinetics and response. Relationship between C_max (A) and AUC_{0–28 d} (B). DOR in patients with a response (C). Patients with an ongoing response at the last follow-up day had higher C_max (A) and AUC_{0–28 d} values (B). Patients with a higher-than-median C_max had a potentially longer DOR than those with lower-than-median C_max, but the differences were not statistically significant (P = 0.463) (C).