Table 2.
Demographic Characteristics of the Test Dataset
| Glaucoma (n = 157) | ||||
|---|---|---|---|---|
| Normal (n = 86) | Early (n = 87) | Advanced (n = 70) | P Value | |
| Age (years) | 62.0 ± 13.3 | 60.3 ± 14.7 | 66.6 ± 11.2 | 0.011a |
| Gender (male/female) | 36/50 | 37/50 | 30/40 | 0.017b |
| Intraocular pressure (mm Hg) | 15.97 ± 3.92 | 15.46 ± 4.46 | 15.00 ± 4.38 | 0.369a |
| Refractive error (diopters) | –0.91 ± 2.57 | –1.37 ± 2.89 | –1.43 ± 2.46 | 0.381a |
| Central corneal thickness (µm) | 550.3 ± 68.6 | 546.5 ± 44.7 | 542.3 ± 36.6 | 0.654a |
| Axial length (cm) | 23.91 ± 1.47 | 24.19 ± 1.69 | 24.13 ± 1.29 | 0.496a |
| VF examination | ||||
| MD (dB) | –1.23 ± 1.24 | –3.16 ± 1.79 | –13.35 ± 7.40 | <0.001c |
| PSD (dB) | 1.71 ± 0.54 | 3.03 ± 1.69 | 8.93 ± 3.27 | <0.001a |
| VF index (%) | 98.7 ± 1.2 | 95.2 ± 3.7 | 63.2 ± 25.0 | <0.001a |
| Zeiss SD-OCT macular ganglion cell analysis | ||||
| Signal strength | 7.63 ± 1.11 | 7.36 ± 8.37 | 7.20 ± 1.12 | 0.048a |
| Average GCIPL thickness (µm) | 80.2 ± 5.3 | 73.1 ± 8.4 | 63.6 ± 8.1 | <0.001c |
| Zeiss SD-OCT ONH and RNFL analysis | ||||
| Signal strength | 7.72 ± 0.95 | 7.45 ± 1.03 | 7.21 ± 1.06 | 0.008a |
| Superior RNFL thickness (µm) | 109.5 ± 14.9 | 94.9 ± 15.9 | 78.6 ± 19.5 | <0.001c |
| Temporal RNFL thickness (µm) | 69.4 ± 12.5 | 65.1 ± 14.1 | 55.5 ± 13.7 | <0.001a |
| Nasal RNFL thickness (µm) | 65.3 ± 9.4 | 64.1 ± 10.1 | 59.3 ± 10.1 | <0.001c |
| Inferior RNFL thickness (µm) | 111.8 ± 18.1 | 87.7 ± 18.3 | 67.1 ± 15.2 | <0.001c |
| Topcon SS-OCT | ||||
| Image-quality score | 59.5 ± 6.1 | 59.1 ± 5.9 | 57.8 ± 6.1 | 0.209a |
| Superior RNFL thickness (µm) | 119.3 ± 18.4 | 97.8 ± 22.9 | 74.2 ± 27.5 | <0.001c |
| Temporal RNFL thickness (µm) | 81.1 ± 13.1 | 72.6 ± 15.5 | 57.9 ± 16.1 | <0.001c |
| Nasal RNFL thickness (µm) | 69.3 ± 14.5 | 64.7 ± 13.3 | 55.6 ± 16.9 | <0.001c |
| Inferior RNFL thickness (µm) | 122.8 ± 21.0 | 90.1 ± 24.2 | 58.1 ± 19.2 | <0.001c |