Table 4.

Unadjusted and adjusted association between psychiatric disorders and odds of hospitalization or death in patients with confirmed COVID-19 infection (n = 2103)

	Hospitalization (OR (95% CI))			Mortality (HR (95% CI))
	Unadjusted	Adjusted (demographics)	Adjusted (fully adjusted)	Unadjusted	Adjusted (demographics)	Adjusted (fully adjusted)
Bipolar disorder (n = 38)
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	4.87 (2.54–9.31), p < 0.0001	5.39 (2.63–11.02), p < 0.0001	4.27 (2.06–8.86), p < 0.0001	2.83 (1.15–6.96), p = 0.0232	2.63 (1.07–6.49), p = 0.0359	2.67 (1.07–6.67), p = 0.0353
Externalizing disorders (n = 238)
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	2.08 (1.55–2.79), p < 0.0001	1.76 (1.27–2.45), p = 0.0007	1.34 (0.93–1.94), p = 0.1142	1.57 (0.93–2.64), p = 0.0916	1.41 (0.83–2.39), p = 0.2084	1.36 (0.78–2.39), p = 0.2832
Internalizing disorders (n = 478)
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	1.18 (0.92–1.50), p = 0.1911	1.04 (0.78–1.37), p = 0.8086	0.85 (0.64–1.13), p = 0.2659	1.60 (1.05–2.44), p = 0.0274	1.27 (0.83–1.95), p = 0.2728	1.13 (0.73–1.76), p = 0.5835
Psychotic disorder (n = 19)
No	Ref	Ref	Ref	–	–	–
Yes	3.46 (1.40–8.57), p = 0.0073	1.98 (0.75–5.21), p = 0.1655	1.49 (0.55–4.04), p = 0.4332	–	–	–
Any disorder (n = 612)
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	1.60 (1.28–2.00), p < 0.0001	1.30 (1.01–1.68), p = 0.0429	1.03 (0.79–1.34), p = 0.8359	1.68 (1.13–2.51), p = 0.0106	1.27 (0.85–1.90), p = 0.2463	1.17 (0.77–1.78), p = 0.4747

Model adjusted for demographics included gender, age, race/ethnicity, location, and payor.

Fully adjusted model included gender, age, race/ethnicity, location, payor, tobacco use, and body mass index.

No Cox models were run for psychotic disorder due to 0% of patients with the outcome of mortality. Bolded values indicate statistical significance between groups.