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Sequential emergence of the seven embryonic and extraembryonic cell types in micropatterned gastruloids
(A and B) UMAP displays of cells at 0, 12, 24, and 44 h of BMP4 treatment clustered by (A) time and (B) cell type.
(C) Bar plot depicting percentage of cell types at the indicated time points.
(D) UMAPs of the seven cell clusters identified at the indicated time points.
(E) Expression of the indicated markers at 0, 12, 24, and 44 h of BMP4 treatment on the UMAP shown in (B).
