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. 2021 Jun 8;49:148–152. doi: 10.1016/j.ajem.2021.05.076

Table 2.

Distinctions between MIS-C and Kawasaki disease [35]

MIS-C Kawasaki disease
  • -

    More commonly affects older children and adolescents (>7 years)

  • -

    GI symptoms very common

  • -

    Myocardial dysfunction and shock more common

  • -

    Inflammatory markers [CRP (12–22 times normal values), ferritin (1–3 times normal values), D-dimer (10–20 times normal values)] more significantly elevated

  • -

    Absolute lymphocyte count and platelet counts are low

  • -

    More commonly affects younger children and infants (<5 years)

  • -

    GI symptoms not common

  • -

    Myocardial dysfunction and shock less common

  • -

    Inflammatory markers (CRP, ferritin, D-dimer) not very elevated

  • -

    Leukocytosis and thrombocytosis are common

MIS-C, Multisystem Inflammatory Syndrome in Children; GI, gastrointestinal; CRP, C reactive protein.