Table 1.
Mutations associated with variants B.1.1.7 (UK), B.1.135 (South Africa), P.1 (Brazil), P.2 (Brazil), B.1.525 (New York), B.1.526 (New York), B.1.427 (California), and B.1.429 (California).
| Gene | B. 1. 1.7 | B.1.135 | P.1 | P.2 | B.1.525 | B.1.526 | B.1.427 | B.1.429 |
|---|---|---|---|---|---|---|---|---|
| Mutation | Mutation | Mutation | Mutation | Mutation | Mutation | Mutation | Mutation | |
| ORF1ab | T1001I | P314F | P314L | L452R | S13I | |||
| A1708D | T2007O | Q1011H | D614G | W152C | ||||
| I2230T | T265I | L452R | ||||||
| L3201P | D614G | |||||||
| SGF 3675‐3677 del | SGF 3675‐3677 del | SGF 3675‐3677 del | 3575‐3677 del | |||||
| nsp5 | L205V | |||||||
| nsp6 | ||||||||
| Spike | H69/V70 del | L18F | A67V | L5F* | ||||
| Y144 del | D80A | H68/V70del | T95I | |||||
| N501Y | D215G | Y144del | D253G | |||||
| A570D | R246I | S477N* | ||||||
| P681H | K417N | K417N | ||||||
| T716I | E484K | E484K | E484K | E484K | E484K* | |||
| S982A | N501Y | N501Y | D614G | |||||
| D118H | A701Y | V1176F | Q677H | *not in all sequences | ||||
| F888L | ||||||||
| Orf8 | Q27stop | |||||||
| R52I | ||||||||
| Y73C | ||||||||
| Nucleocapsid | D3L | A119S | A12G | |||||
| S235F | R203K | T205I | ||||||
| G204R | ||||||||
| M234I |