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. 2021 May 31;13(6):e14062. doi: 10.15252/emmm.202114062

Table 3.

United Kingdom.

Position Location Mutation 01/19/2020–01/20/2021
Total Count Percentage
66nt 5´UTR C → T 2,787 3.9
204nt G → T 20,770 29.07
241nt C → T 69,160 96.81
445nt ORF1ab polyprotein → leader protein T → C 34,505 48.3
1,163nt nsp2 A → T 2,544 3.56
1,210nt G → T 1,440 2.02
1,513nt C → T 1,528 2.14
1,947nt T → C 1,576 2.21
1,987nt A → G 3,018 4.22
3,037nt nsp3 C → T 69,231 96.91
3,256nt T → C 2,523 3.53
4,002nt C → T 1,519 2.13
4,543nt C → T 1,516 2.12
6,286nt C → T 34,650 48.5
6,807nt C → T 2,220 3.11
7,528nt C → T 1,524 2.13
7,926nt C → T 2,818 3.94
8,683nt nsp4 C → T 2,189 3.06
9,745nt C → T 3,640 5.1
9,802nt G → T 1,449 2.03
10,097nt 3C‐like proteinase G → A 2,954 4.13
10,870nt G → T 3,186 4.46
11,083nt nsp6 G → T 5,734 8.03
11,396nt C → T 2,286 3.2
11,533nt A → G 1,960 2.74
11,781nt A → G 2,368 3.31
12,067nt nsp7 G → T 1,709 2.39
13,536nt RNA‐dependent RNA polymerase C → T 1,502 2.1
14,202nt G → T 2,522 3.53
14,408nt C → T 69,237 96.92
14,805nt C → T 1,860 2.6
15,406nt G → T 2,077 2.91
18,877nt 3'‐to‐5' exonuclease C → T 3,827 5.36
19,542nt G → T 2,582 3.61
19,718nt endoRNAse C → T 2,645 3.7
20,268nt A → G 1,999 2.8
21,255nt 2'‐O‐ribose methyltransferase G → C 34,494 48.28
21,575nt Spike glycoprotein C → T 1,502 2.1
21,614nt C → T 17,561 24.58
21,637nt C → T 2,697 3.78
22,227nt C → T 34,855 48.79
22,346nt G → T 2,244 3.14
22,377nt C → T 1,518 2.12
22,388nt C → T 2,540 3.56
22,444nt C → T 2,085 2.92
22,992nt G → A 1,636 2.29
23,403nt A → G 69,262 96.95
23,731nt C → T 2,940 4.12
24,334nt C → T 10,442 14.62
25,563nt ORF3a G → T 5,774 8.08
25,614nt C → T 2,737 3.83
26,060nt C → T 2,632 3.68
26,144nt G → T 1,748 2.45
26,424nt Envelope protein T → C 1,957 2.74
26,735nt Membrane glycoprotein C → T 3,760 5.26
26,801nt C → G 34,459 48.24
27,769nt ORF7b C → T 2,706 3.79
27,944nt ORF8 C → T 25,177 35.24
28,169nt A → G 2,693 3.77
28,854nt Nucleocapsid phosphoprotein C → T 3,683 5.16
28,881nt G → A 23,975 33.56
28,882nt G → A 23,947 33.52
28,883nt G → C 23,946 33.52
28,932nt C → T 34,536 48.34
29,227nt G → T 2,566 3.59
29,366nt C → T 1,743 2.44
29,466nt C → T 2,578 3.61
29,555nt At upstream downstream region of ORF10 ORF9 C → T 1,466 2.05
29,645nt ORF10 G → T 34,684 48.55
29,771nt 3´UTR A → G 2,475 3.46

Details of the mutant analyses of 7,144 SARS‐CoV‐2 isolates for deviations from the Wuhan reference sequence. These sequences were deposited in the GISAID initiative between 01/19/2020 and 01/20/2021. For design of Tables, see legend to Table 5.