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. 2021 Feb 17;22(6):1272–1280. doi: 10.1093/pm/pnab065

Table 4.

Effects of the LIRE intervention on utilization of lumbar, sacral, or thoracic spine surgery over 18-month follow-up

Any
Adjusted Proportions
Control (n = 117,455) Intervention (n = 121,431) OR‖ (95% CI) P
Primary outcome (Aim 2)
 Any spine surgery* 3.2% 3.1% 0.99 (0.91–1.07) 0.74
Secondary outcomes (Aim 2)
 Fusion 1.1% 1.1% 1.01 (0.89–1.14) 0.85§
 Decompression 2.9% 2.8% 0.97 (0.88–1.06) 0.47§
*

Any spine surgery includes decompression surgery, spinal fusion or proxies for spine fusion, or other surgeries involving the lumbar, sacral, or thoracic spine.

Statistical significance defined as P < 0.05.

Spinal fusion or proxies for spinal fusion (e.g., disc arthroplasty). Fusion may or may not have also involved decompression.

§

Statistical significance defined as P < 0.025 (with Bonferroni correction accounting for two individual surgical spine procedures).

Models adjusting for fixed effects (site, clinic size tertile, computed tomography vs. magnetic resonance imaging, Charlson Comorbidity category [0, 1, 2, 3+], site-specific time [linear], gender, age range [<40, 40–60, >60]) and random effects (clinic [intercept and treatment] and provider [intercept only]).