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. 2021 May 24;23(5):e25609. doi: 10.2196/25609

Table 2.

Results of the main analyses (based on 2500 bootstrap simulations) based on societal and public health care perspectives.

Type of analysis Incremental costs (in €), mean (95% CI)a Incremental effects, mean (95% CI)a ICERb, mean (95% CI) Distribution over the cost-effectiveness plane (%)




NEQc NWQd SEQe SWQf
Societal perspective

CEAg (SFS)h –1121 (–3012 to 64) 0.30 (0.16 to 0.43) dominanti 6 94

CUAj (SF-6D QALY)k –1121 (–3012 to 64) 0.0183 (–0.0182 to 0.0185) dominant 6 94
Public health care perspective

CEA (SFS) 189 (–97 to 350) 0.30 (0.16 to 0.43) 650 (–215 to 1652) 94 6

CUA (SF-6D QALY) 189 (97 to 350) 0.0183 (0.0182 to 0.0185) 11,285 (–1750 to 27,493) 96 4

a95% CIs in this column were bias-corrected and accelerated.

bICER: incremental cost-effectiveness ratio.

cNEQ: north–east quadrant.

dNWQ: north–west quadrant.

eSEQ: south–east quadrant.

fSWQ: south–west quadrant.

gCEA: cost-effectiveness analysis.

hSFS: symptom-free status (0=no, 1=yes).

idominant: The intervention resulted in higher effects at lower costs compared to the control condition.

jCUA: cost–utility analysis.

kSF-6D QALY: 6D Health State Short Form quality-adjusted life years based on the SF-12.