Table 8.
The latest day of seroconversion (when the last animal of the study seroconverted) in the experimental studies where non‐vaccinated, naive animals were infected through direct contact with infected animals with FMDV serotype O. The antibodies were detected using different laboratory methods
| Laboratory method | Animals | Latest day of seroconversion (dpc) | References |
|---|---|---|---|
| VNT | Cattle | 7 | Cox et al. (2005) |
| VNT (CO ≥ 1/45) | Cattle | 20 | Paiba et al. (2004) |
| VNT (CO ≥ 1/45) | Sheep | 10 | Paiba et al. (2004) |
| SPCE (CO ≥ 60 PI) | Cattle | 12 | Parida et al. (2005) |
| SPCE (CO ≥ 60 PI) | Cattle | 20 | Paiba et al. (2004) |
| SPCE (CO ≥ 60 PI) | Sheep | 8 | Paiba et al. (2004) |
| SPCE (CO ≥ 60 PI) | Pig | 9 | Paiba et al. (2004) |
| Indirect 2B peptide ELISA (CO: OD > 0.67) | Cattle | 14 | Parida et al. (2005) |
| LPBE(CO = 50% PB at serum dilution 1/40) | Pigs | 4 | Alexandersen et al. (2001) |
| NSP ELISA (commercial tests: UBI, Cedi, Bommeli) CO according to the manufacturer | Cattle | Cedi: 28 Bommeli: 16 UBI: 16 | Parida et al. (2005) |
| NSP ELISA (Cedi) and in house ELISA | Sheep | 151 | Madhanmohan et al. (2010) |
| Goats | 101 |
dpc: days post contact with infected animals; LPBE: Liquid‐phase blocking ELISA; NSP: Non‐Structural Protein Antibody Test; SPCE: Solid‐phase Competition ELISA; VNT: Virus Neutralisation Test; PI: Percentage Inhibition; PB: Percentage Blocking; OD: optical density; CO: cut‐off.
1
Sampling every 5 days.