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. 2021 Jun 7;181(8):1055–1063. doi: 10.1001/jamainternmed.2021.2617

Table 3. Frequencies, Events, and Event Rates per 1000 Person-Years of Subsequent Clinical Fracture,a Stratified by Whether the Initial Fracture Was Traumatic or Nontraumatic and Baseline Age.

Characteristic Subsequent fracture by initial fracture trauma
Traumatic Nontraumatic Unknown traumatic
No. (%) Events Rate per 1000 (95% CI) No. Events Rate per 1000 (95% CI) No. (%) Events Rate per 1000 (95% CI)
All participants 1624 (100.0) 137 20.3 (17.2-24.0) 3891 (100.1) 398 27.0 (24.5-29.8) 1627 (100.0) 186 30.2 (26.2-34.9)
Age, y
<55 147 (9.1) 8 11.9 (5.9-23.8) 311 (8.0) 15 11.6 (7.0-19.3) 116 (7.1) 10 18.5 (9.1-34.4)
55-59 327 (20.1) 14 9.9 (5.9-16.8) 552 (14.2) 38 17.08 (12.3-23.3) 220 (13.6) 11 12.1 (6.7-21.9)
60-64 384 (23.7) 26 16.3 (11.1-23.9) 768 (19.7) 58 19.3 (14.9-25.0) 346 (21.3) 31 23.9 (16.8-34.0)
65-69 377 (23.2) 38 23.7 (17.2-32.5) 993 (25.5) 95 25.9 (21.2-31.7) 411 (25.1) 49 32.0 (24.2-42.3)
70-74 258 (15.9) 34 35.2 (25.2-49.3) 809 (20.8) 104 34.9 (28.8-42.3) 336 (20.7) 41 34.4 (25.3-46.7)
≥75 131 (8.1) 17 34.2 (21.2-55.0) 458 (11.8) 88 57.2 (46.4-70.5) 196 (12.1) 44 63.9 (47.5-95.9)
a

Fracture sites included lower extremity (ankle, hip, patella, pelvis, shaft of femur, tibia/fibula, tibial plateau), upper extremity (carpal, elbow, lower end of humerus, radius/ulna, upper end of humerus, shaft of humerus, upper radius/ulna), and spine (lumbar spine, thoracic spine) fractures.